Baricitinib|Macitentan|Brexpiprazole|Bupropion|Apixaban|Baricitinib|Methotrexate supplier

PRODUCTS

APIs

Name	CAS	Status	Use
Axitinib	319460-85-0	pilot phase	Anti-tumor drugs
Isavuconazole\|241479-67-4	241479-67-4	pilot phase	Isavuconazole API
posaconazole\|171228-49-2	\|171228-49-2	pilot phase	posaconazole
Adapalene 106685-40-9	106685-40-9	pilot phase	Adapalene API
Tofacitinib citrate\|540737-29-9	540737-29-9	pilot phase	Tofacitinib citrate Rheumatoid Arthritis Drugs
Ganciclovir\|82410-32-0	82410-32-0	pilot phase	Ganciclovir Anti-viral Drugs
VX 770\|873054-44-5	873054-44-5	pilot phase	VX 770 Respiratory Durgs
Selexipag\|475086-01-2	475086-01-2	pilot phase	Selexipag Respiratory Durgs
Lorcaserin Hydrochloride\|856681-05-5	856681-05-5	commercial quantity	Lorcaserin weight loss
Bupropion\|31677-93-7\|34841-39-9\|34911-55-2	31677-93-7	commercial quantity	a medication primarily used as an antidepressant and smoking cessation aid.
Bupropion\|31677-93-7\|34841-39-9\|34911-55-2	34911-55-2	commercial quantity	a medication primarily used as an antidepressant and smoking cessation aid.
Ruxolitinib\|1092939-17-7	1092939-17-7	pilot phase	Ruxolitinib API
Ipragliflozin\|761423-87-4	761423-87-4	pilot phase	Ipragliflozin
Nintedanib\|656247-17-5	656247-17-5	pilot phase	Nintedanib API
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Intermediates

Name	CAS	Status	Use
N-Methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-6-yl]thio]benzamide\|885126-35-2	885126-35-2	pilot phase	Axitinib intermediates
(E)-6-Iodo-3-[2-(pyridin-2-yl)ethenyl]-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole\|886230-77-9	886230-77-9	pilot phase	Axitinib intermediates
(E)-3-[2-(Pyridin-2-yl)ethenyl]-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-6-amine\|886230-76-8	886230-76-8	pilot phase	Axitinib intermediates
2-Mercapto-N-methylbenzamide\|20054-45-9	20054-45-9	pilot phase	Axitinib intermediates
N-Methyl-N-[(3R,4R)-4-methyl-1-(phenylmethyl)-3-piperidinyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine\|477600-73-0	477600-73-0	pilot phase	Tofacitinib citrate intermediates
2,4-Dichloro-1H-pyrrolo[2,3-d]pyrimidine\|90213-66-4	90213-66-4	pilot phase	Tofacitinib citrate intermediates
4-Chloropyrrolo[2,3-d]pyrimidine\|3680-69-1	3680-69-1	pilot phase	Tofacitinib citrate intermediates
4-Chloro-7-(4-methylphenylsulfonyl)-7H-pyrrolo[2,3-d]pyrimidine\|479633-63-1	479633-63-1	pilot phase	Tofacitinib citrate intermediates
(3R,4R)-N,4-Dimethyl-1-(phenylmethyl)-3-piperidinamine hydrochloride\|1062580-52-2	1062580-52-2	pilot phase	Tofacitinib citrate intermediates
4-[(5,6-Diphenylpyrazinyl)(1-methylethyl)amino]-1-butanol\|475086-75-0\|Selexipag intermediates	475086-75-0	pilot phase	Selexipag intermediates
2-bromo-N-methylsulfonylacetamide\|59504-75-5\|Selexipag intermediates	59504-75-5	pilot phase	Selexipag intermediates
N-(chloracetyl)methanesulfonamide\|202658-88-6\|Selexipag intermediates	202658-88-6	pilot phase	Selexipag intermediates
5-Chloro-2,3-diphenylpyrazine\|41270-66-0\|Selexipag intermediates	41270-66-0	pilot phase	Selexipag intermediates
4-(IsopropylaMino)butanol\|42042-71-7\|Selexipag intermediates	42042-71-7	pilot phase	Selexipag intermediates
1-Benzhydryl-3-azetidinol hydrochloride	90604-02-7	commercial quantity	Use as the intermediates
1-BOC-PIPERAZINE\|57260-71-6\|Brexpiprazole intermediate	57260-71-6	commercial quantity	Brexpiprazole intermediates
2-(Aminoacetylamino)-3-(o-chlorobenzoyl)-5-ethylthiophene\|50509-09-6	50509-09-6	commercial quantity	chemical intermediates
(2-amino-5-ethylthiophen-3-yl)(2-chlorophenyl)methanone\|50508-60-6	50508-60-6	commercial quantity	Chemical intermediates
Isopropoxyboronic acid pinacol ester	61676-62-8	pilot phase	pharma intermediates
3ALPHA-HYDROXY-7-OXO-5BETA-CHOLANIC ACID\|4651-67-6\|obeticholic acid intermediate	4651-67-6	pilot phase	obeticholic acid intermediates
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Paxlovid

Name	CAS	Status	Use
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Molnupiravir |EIDD-2801

Name	CAS	Status	Use
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Baricitinib

Name	CAS	Status	Use
Baricitinib\|1187594-09-7	1187594-09-7	pilot phase	Baricitinib API
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Macitentan

Name	CAS	Status	Use
Macitentan\|441798-33-0	441798-33-0	pilot phase	Macitentan API
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Brexpiprazole

Name	CAS	Status	Use
Brexpiprazole\|913611-97-9	913611-97-9	commercial quantity	Brexpiprazole API
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Apixaban

Name	CAS	Status	Use
Apixaban\|503612-47-3	503612-47-3	commercial quantity	Apixaban API
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Lurasidone

Name	CAS	Status	Use
Lurasidone\|367514-87-2	367514-87-2	commercial quantity	Lurasidone API
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LX-4211

Name	CAS	Status	Use
LX4211\|1018899-04-1	1018899-04-1	pilot phase	Sotagliflozin、LX4211 API
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Ipragliflozin

Name	CAS	Status	Use
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Methotrexate

Name	CAS	Status	Use
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Methotrexate intermediates

Name	CAS	Status	Use
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Molnupiravir intermediate

Name	CAS	Status	Use
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Paxlovid intermediate

Name	CAS	Status	Use
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Macitentan intermediates

Baricitinib intermediates

Name	CAS	Status	Use
2-(1-(ethylsulfonyl)-3-(4-(7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)azetidin-3-yl)acetonitrile	1187594-13-3	commercial quantity	Use as the Baricitinib intermediates
(4-(1H-pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)methyl pivalate	1146629-77-7	commercial quantity	Use as the Baricitinib intermediates
[4-[1-(1-ethoxyethyl)-1H-pyrazol-4-yl]-7H-pyrrolo[2,3-d]pyrimidin-7-yl]methyl	1146629-76-6	commercial quantity	Baricitinib intermediates
(4-(1-(3-(cyanomethyl)-1-(ethylsulfonyl)azetidin-3-yl)-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)methyl pivalate	1187595-90-9	commercial quantity	Baricitinib intermediates
2-(azetidin-3-ylidene)acetonitrile (hydrochloride)\|1314910-43-4\|Baricitinib intermediate	1314910-43-4	commercial quantity	Baricitinib intermediates
4-(1H-PYRAZOL-4-YL)-7-((2-(TRIMETHYLSILYL)ETHOXY)METHYL)-7H-PYRROLO[2,3-D]PYRIMIDINE\|941685-27-4\|Baricitinib intermediate	941685-27-4	commercial quantity	Baricitinib intermediates
2-(1-(ethylsulfonyl)azetidin-3-ylidene)acetonitrile\|1187595-85-2\|Baricitinib intermediate	1187595-85-2	commercial quantity	Baricitinib intermediates
1-Boc-3-(cyanomethylene)azetidine\|1153949-11-1\|Baricitinib intermediate	1153949-11-1	commercial quantity	Baricitinib intermediates
1-(1-ethoxyethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole\|1029716-44-6\|Baricitinib intermediate	1029716-44-6	commercial quantity	Baricitinib intermediates
4-(1-(1-ethoxyethyl)-1H-pyrazol-4-yl)-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine\|1187595-88-5\|Baricitinib intermediate	1187595-88-5	commercial quantity	Baricitinib intermediates
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Brexpiprazole intermediates

Name	CAS	Status	Use
Piperazine, 1-benzo[b]thien-4-yl-, hydrochloride\|913614-18-3\|Brexpiprazole intermediate	913614-18-3	pilot phase	Brexpiprazole intermediates
7-Hydroxyquinolinone\|70500-72-0\|Brexpiprazole intermediate	70500-72-0	commercial quantity	Brexpiprazole intermediates
N-(CINNAMOYL)-3-METHOXYANILINE\|127033-74-3\|Brexpiprazole intermediate	127033-74-3	pilot phase	Brexpiprazole intermediates
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Apixaban Intermediates

Name	CAS	Status	Use
1-(4-Aminophenyl)-5,6-dihydro-3-(4-morpholinyl)-2(1H)-pyridinone	1267610-26-3	commercial quantity	Apixaban Intermediates
ethyl6-(4-aMinophenyl)-1-(4-Methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrao	503615-07-4	pilot phase	Apixaban Intermediates
4,5,6,7-Tetrahydro-1-(4-methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester	536759-91-8	pilot phase	Apixaban Intermediates
3-(4-Morpholinyl)-1-(4-nitrophenyl)-5,6-dihydro-2(1H)-pyridinone	503615-03-0	commercial quantity	Apixaban Intermediates
5,6-Dihydro-3-(4-morpholinyl)-1-[4-(2-oxo-1-piperidinyl)phenyl]-2(1H)-pyridinone	545445-44-1	commercial quantity	Apixaban Intermediates
3-Chloro-5,6-dihydro-1-(4-nitrophenyl)-2(1H)-pyridinone	536760-29-9	commercial quantity	Apixaban Intermediates
Chloro[(4-methoxyphenyl)hydrazono]acetic acid ethyl ester	27143-07-3	commercial quantity	Apixaban intermediate
1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester	503614-91-3	pilot phase	Apixaban Intermediates
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Lurasidone intermediates

Ipragliflozin intermediate

Name	CAS	Status	Use
Benzo[b]thiophene, 2-[(5-broMo-2-fluorophenyl)Methyl]-\|1034305-17-3\|Ipragliflozin intermediate	1034305-17-3	pilot phase	Ipragliflozin intermediate
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LX-4211 intermediates

Name	CAS	Status	Use
4-Iodo-1-chloro-2-(4-ethoxybenzyl)benzene\|1103738-29-9\|LX4211 intermediate	1103738-29-9	pilot phase	LX4211 intermediates
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Add: No.507,Building 4,Tianhua Street, Biomedicine industrial Base,Daxing District,Beijing,China Tel: +86-010-60279497

Name	CAS	Status	Use
5-bromo-2-chloro-4'-ethoxydiphenylmethane	461432-23-5	commercial quantity	Use as the Dapagliflozin intermediates
PropylsulfaMide\|147962-41-2\|Macitentan intermediate	147962-41-2	commercial quantity	Macitentan intermediates
PyriMidine, 5-(4-broMophenyl)-4,6-dichloro-\|146533-41-7\|Macitentan intermediate	146533-41-7	commercial quantity	Macitentan intermediates
2-(4-Bromo-phenyl)-malonic acid dimethyl ester\|149506-35-4\|Macitentan intermediates	149506-35-4	pilot phase	Macitentan intermediates
5-(4-Bromophenyl)-4,6-pyrimidinediol\|706811-25-8\|Macitentan intermediates	706811-25-8	pilot phase	Macitentan intermediates
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Name	CAS	Status	Use
(3aR,4S,7R,7aS) 4,7-Methano-1H-isoindole-1,3(2H)-dione	14805-29-9	commercial quantity	Lurasidone intermediates
(3aR,7aR)-4'-(1,2-Benzisothiazol-3-yl)octahydrospiro[2H-isoindole-2,1'-piperaziniuM] Methanesulfonate	186204-37-5	pilot phase	Lurasidone intermediates
(R,R)-1,2-bis(methanesulfonyloxymethyl)cyclohexane	186204-35-3	pilot phase	Lurasidone intermediates
(1R,2R)-1,2-CYCLOHEXANEDIMETHANOL	65376-05-8	pilot phase	Lurasidone intermediates
(1R,2R)-(-)-1,2-CYCLOHEXANEDICARBOXYLIC ACID	46022-05-3	pilot phase	Lurasidone intermediates
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APIs

Intermediates

Axitinib

319460-85-0

Isavuconazole|241479-67-4

241479-67-4

posaconazole|171228-49-2

|171228-49-2

Adapalene 106685-40-9

106685-40-9

Tofacitinib citrate|540737-29-9

540737-29-9

Ganciclovir|82410-32-0

82410-32-0

VX 770|873054-44-5

873054-44-5

Selexipag|475086-01-2

475086-01-2

Lorcaserin Hydrochloride|856681-05-5

856681-05-5

Bupropion|31677-93-7|34841-39-9|34911-55-2

31677-93-7

Bupropion|31677-93-7|34841-39-9|34911-55-2

34911-55-2

Ruxolitinib|1092939-17-7

1092939-17-7

Ipragliflozin|761423-87-4

761423-87-4

Nintedanib|656247-17-5

656247-17-5

N-Methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-6-yl]thio]benzamide|885126-35-2

885126-35-2

(E)-6-Iodo-3-[2-(pyridin-2-yl)ethenyl]-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole|886230-77-9

886230-77-9

(E)-3-[2-(Pyridin-2-yl)ethenyl]-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-6-amine|886230-76-8

886230-76-8

2-Mercapto-N-methylbenzamide|20054-45-9

20054-45-9

N-Methyl-N-[(3R,4R)-4-methyl-1-(phenylmethyl)-3-piperidinyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine|477600-73-0

477600-73-0

2,4-Dichloro-1H-pyrrolo[2,3-d]pyrimidine|90213-66-4

90213-66-4

4-Chloropyrrolo[2,3-d]pyrimidine|3680-69-1

3680-69-1

4-Chloro-7-(4-methylphenylsulfonyl)-7H-pyrrolo[2,3-d]pyrimidine|479633-63-1

479633-63-1

(3R,4R)-N,4-Dimethyl-1-(phenylmethyl)-3-piperidinamine hydrochloride|1062580-52-2

1062580-52-2

4-[(5,6-Diphenylpyrazinyl)(1-methylethyl)amino]-1-butanol|475086-75-0|Selexipag intermediates

475086-75-0

2-bromo-N-methylsulfonylacetamide|59504-75-5|Selexipag intermediates

59504-75-5

N-(chloracetyl)methanesulfonamide|202658-88-6|Selexipag intermediates

202658-88-6

5-Chloro-2,3-diphenylpyrazine|41270-66-0|Selexipag intermediates

41270-66-0

4-(IsopropylaMino)butanol|42042-71-7|Selexipag intermediates

42042-71-7

1-Benzhydryl-3-azetidinol hydrochloride

90604-02-7

1-BOC-PIPERAZINE|57260-71-6|Brexpiprazole intermediate

57260-71-6

2-(Aminoacetylamino)-3-(o-chlorobenzoyl)-5-ethylthiophene|50509-09-6

50509-09-6

(2-amino-5-ethylthiophen-3-yl)(2-chlorophenyl)methanone|50508-60-6

50508-60-6

Isopropoxyboronic acid pinacol ester

61676-62-8

3ALPHA-HYDROXY-7-OXO-5BETA-CHOLANIC ACID|4651-67-6|obeticholic acid intermediate

4651-67-6

Baricitinib|1187594-09-7

1187594-09-7

Macitentan|441798-33-0

441798-33-0

Brexpiprazole|913611-97-9

913611-97-9

Apixaban|503612-47-3

503612-47-3

Lurasidone|367514-87-2

367514-87-2